Rogan began a career in comedy in August 1988 in the Boston area. After relocating to Los Angeles in 1994, Rogan signed an exclusive developmental deal with Disney and appeared as an actor on several television shows including Hardball and NewsRadio. In 1997, he started working for the Ultimate Fighting Championship (UFC) as an interviewer and color commentator. Rogan released his first comedy special in 2000. In 2001, Rogan put his comedy career on hold after becoming the host of Fear Factor and would resume his stand-up career shortly after the show's end in 2006. In 2009, Rogan launched his podcast The Joe Rogan Experience. In various episodes of the show as well as other platforms, Rogan has advocated for "long-form media."
Rogan is not affiliated with any political party, but has been described as mostly having libertarian views. He has described himself as being "pretty liberal" and supports gay marriage, gay rights, women's rights, recreational drug use, universal healthcare, and universal basic income, while also supporting the Second Amendment. He also has criticized American foreign policy of military adventurism. He endorsed Ron Paul in the 2012 U.S. presidential campaign and Gary Johnson in the 2016 U.S. presidential campaign. Rogan has publicly supported Tulsi Gabbard and encouraged her to run for U.S. presidency in 2020. On January 21, 2020, Rogan said he would "probably" vote for Bernie Sanders in the 2020 Democratic primary, adding, "He’s been insanely consistent his entire life."
The Joe Rogan Experience has featured many members of what has been dubbed the Intellectual Dark Web, such as Eric Weinstein, Managing Director of Thiel Capital, a firm that provides venture capital investments.
Rogan supports the legalized use of cannabis and believes it holds numerous benefits. He hosted the documentary film, The Union: The Business Behind Getting High, and was featured in Marijuana: A Chronic History and The Culture High. He also supports the use of LSD, psilocybin mushrooms, and DMT toward the exploration and enhancement of consciousness, as well as introspection. He was the presenter in the 2010 documentary, DMT: The Spirit Molecule.
Rogan is an avid hunter and is part of the "Eat What You Kill" movement, which attempts to move away from factory farming and the mistreatment of animals raised for food.
Rogan is opposed to routine infant circumcision and has claimed there is a lack of significant scientific evidence for any benefits to the practice, which he considers not entirely different from female genital mutilation due to its non-consensual nature.
Rogan has an interest in sensory deprivation and using an isolation tank. He has stated that his personal experiences with meditation in isolation tanks has helped him explore the nature of consciousness as well as improve his performance in various physical and mental activities and overall well-being.
In January 2020 Joe Rogan went on an all-meat diet called the carnivore diet.